BEST provides solutions to problems caused by improper and fragmented pre-clinical testing.
BEST uses integrated approach, based on a fundamental principle: there is no specimen response before the stimulus applied.
BEST experimental data are post-processed without use of an explicit material model, based on idempotent analysis (patents pending). There BEST integrates specimen history and extracts unknown values.
BEST is performed under controlled conditions with required coherent stimuli. It assesses changes in properties of the specimen in time, phase and stimulus domains.
BEST invariant parameters show the position and the direction of development of your biomaterial and provide solid data for its optimization.
BEST aims to non-destructively characterize specimens at coherent conditions, closer to physiological reality.
Does not require assumptions on material linearity, specimen homogeneity, geometric and intermode linearities
Testing comprises high-output coherent screening, incorporating specimen history dependence
Non-destructive evaluation in most cases - you may reprocess the specimen
No need for using complex numbers algebra or transforms
Previous data maybe reprocessed without need for new experiments
Depending on the purpose, BEST can evaluate many readouts (in many cases, from a single specimen or test), such as:
Characteristic times of the material reactivity
Channel size (effective size) for porous and permeable specimens
Compliance to different applied stresses
Dynamic true modulus
Fluid diffusivity / mobility (for fluid-filled specimens) in statics and dynamics
Fluid source/rate (for fluid filled specimens) in statics and dynamics
Injection kinetics and injectability (e.g. from a prefilled syringes into tissue phantoms)
Material permeability / permittivity
Material memory function (in statics and dynamics)
Material properties map (invariant values)
Potential changes in the specimen fine structure and properties
Shear modulus (in a special sample holder setup)
Slope modulus (within compliance analysis)
Swelling pressure / kinetics
True stress and strain
Viscosity (real time and invariants)
BEST measures properties for the purpose - the same material may have different properties vs. conditions like media, temperature, etc., so it is important the values are exactly what you need for that medical application your biomaterial has its intended purpose.